A PI4KIIIα inhibitor (IC50 = 5.01 nM); selective for PI4KIIIα over PI4Kβ, PI3Kα, PI3Kβ, PI3Kδ, and PI4Kγ (IC50s = 1,000, 2,512, 7,943, 2,512, and 2,512 nM, respectively); inhibits replication of HCV genotypes 1a, 1b, and 2a in a cell-based replicon assay (IC50s = 12.6, 2.51, and 12.6 nM, respectively)